DETERMINATION OF THE MINIMUM INFECTIVE DOSE OF CRYPTOSPORIDIUM
PARVUM OOCYSTS IN VERVET MONKEYS (Cercopithecus aethiops). DRAFT
FINAL REPORT TO THE DEPARTMENT OF THE ENVIRONMENT IN PARTIAL
FULFILMENT OF WRc CONTRACT NUMBER ESL 9517
Report No DWI0375/12
Cryptosporidium oocysts derived from symptomatic human cases were administered orally to adult, juvenile and infant vervet monkeys (Cercopithecus aethiops) at doses of either 1 x 10^5 or 1 x 10^4 per os. None of the animals infected developed discernible signs of cryptosporidiosis during a follow up period of four to six weeks. Similarly no oocysts were detected in the faeces of any animal during a follow up period of four to six weeks.
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